Sunday , September 26 2021
Home / David Henderson /Henderson and Hooper on Ivermectin

Henderson and Hooper on Ivermectin

Summary:
On July 28 (electronic) and July 29 (print edition), the Wall Street Journal published an article by Charley Hooper and me on ivermectin. At our request, the Journal published a correction that we provided on the evening of July 28 and our letter to the editor. The letter to the editor is appended below. Because over 30 days have passed, I’m free to upload the whole article. Here’s the article: The Food and Drug Administration claims to follow the science. So why is it attacking ivermectin, a medication it certified in 1996? Earlier this year the agency put out a special warning that “you should not use ivermectin to treat or prevent COVID-19.” The FDA’s statement included words and phrases such as “serious harm,” “hospitalized,” “dangerous,” “very dangerous,”

Topics:
David Henderson considers the following as important: , , ,

This could be interesting, too:

David Henderson writes Preach What You Practice

David Henderson writes Boudreaux on Government’s Nature

Don Boudreaux writes Some Covid Links

David Henderson writes Dr. Moreno Comes Through

Henderson and Hooper on Ivermectin

On July 28 (electronic) and July 29 (print edition), the Wall Street Journal published an article by Charley Hooper and me on ivermectin. At our request, the Journal published a correction that we provided on the evening of July 28 and our letter to the editor. The letter to the editor is appended below.

Because over 30 days have passed, I’m free to upload the whole article.

Here’s the article:

The Food and Drug Administration claims to follow the science. So why is it attacking ivermectin, a medication it certified in 1996?

Earlier this year the agency put out a special warning that “you should not use ivermectin to treat or prevent COVID-19.” The FDA’s statement included words and phrases such as “serious harm,” “hospitalized,” “dangerous,” “very dangerous,” “seizures,” “coma and even death” and “highly toxic.” Any reader would think the FDA was warning against poison pills. In fact, the drug is FDA-approved as a safe and effective antiparasitic.

Ivermectin was developed and marketed by Merck while one of us (Mr. Hooper) worked there years ago. William C. Campbell and Satoshi Omura won the 2015 Nobel Prize for Physiology or Medicine for discovering and developing avermectin, which Mr. Campbell and associates modified to create ivermectin.

Ivermectin is on the World Health Organization’s List of Essential Medicines. Merck has donated four billion doses to prevent river blindness and other diseases in Africa and other places where parasites are common. A group of 10 doctors who call themselves the Front Line Covid-19 Critical Care Alliance have said ivermectin is “one of the safest, low-cost, and widely available drugs in the history of medicine.”

Ivermectin fights 21 viruses, including SARS-CoV-2, the cause of Covid-19. A single dose reduced the viral load of SARS-CoV-2 in cells by 99.8% in 24 hours and 99.98% in 48 hours, according to a June 2020 study published in the journal Antiviral Research.

Some 70 clinical trials are evaluating the use of ivermectin for treating Covid-19. The statistically significant evidence suggests that it is safe and works for both treating and preventing the disease.

In 115 patients with Covid-19 who received a single dose of ivermectin, none developed pneumonia or cardiovascular complications, while 11.4% of those in the control group did. Fewer ivermectin patients developed respiratory distress (2.6% vs. 15.8%); fewer required oxygen (9.6% vs. 45.9%); fewer required antibiotics (15.7% vs. 60.2%); and fewer entered intensive care (0.1% vs. 8.3%). Ivermectin-treated patients tested negative faster, in four days instead of 15, and stayed in the hospital nine days on average instead of 15. Ivermectin patients experienced 13.3% mortality compared with 24.5% in the control group.

Moreover, the drug can help prevent Covid-19. One 2020 article in Biochemical and Biophysical Research Communications looked at what happened after the drug was given to family members of confirmed Covid-19 patients. Less than 8% became infected, versus 58.4% of those untreated.

Despite the FDA’s claims, ivermectin is safe at approved doses. Out of four billion doses administered since 1998, there have been only 28 cases of serious neurological adverse events, according to an article published this year in the American Journal of Therapeutics. The same study found that ivermectin has been used safely in pregnant women, children and infants.

If the FDA were driven by science and evidence, it would give an emergency-use authorization for ivermectin for Covid-19. Instead, the FDA asserts without evidence that ivermectin is dangerous.

At the bottom of the FDA’s warning against ivermectin is this statement: “Meanwhile, effective ways to limit the spread of COVID-19 continue to be to wear your mask, stay at least 6 feet from others who don’t live with you, wash hands frequently, and avoid crowds.” Is this based on the kinds of double-blind studies that the FDA requires for drug approvals? No.

Correction
This article has been edited to remove a reference to a study of 200 healthcare workers by Ahmed Elgazzar of Benha University in Egypt. Messrs. Henderson and Hooper relied on a summary of studiespublished in the American Journal of Therapeutics. They learned after publication that this study has been retracted because of charges of data manipulation.

Our letter to the editor, which ran in the July 29 electronic edition (July 30 print):

We, the authors of “Why Is the FDA Attacking a Safe, Effective Drug?” (op-ed, July 29), have egg on our faces. Relying on a summary of studies published in the American Journal of Therapeutics, we quoted the results from a study of 200 healthcare workers. After our article was published, we learned that this study, by Ahmed Elgazzar of Benha University in Egypt, has recently been retracted due to serious charges of data manipulation.

We retract the part of our article that relied on the data from Dr. Elgazzar’s study. But the broader point stands: There’s strong evidence of ivermectin’s efficacy in treating Covid-19.

David R. Henderson

Charles L. Hooper
Grass Valley, Calif.

David Henderson
David R. Henderson (born November 21, 1950) is a Canadian-born American economist and author who moved to the United States in 1972 and became a U.S. citizen in 1986, serving on President Ronald Reagan's Council of Economic Advisers from 1982 to 1984.[1] A research fellow at Stanford University's Hoover Institution[2] since 1990, he took a teaching position with the Naval Postgraduate School in Monterey, California in 1984, and is now a full professor of economics.[3]

Leave a Reply

Your email address will not be published. Required fields are marked *